SS-31
SS-31 Peptide , also known as Elamipretide, is a synthetic peptide that targets mitochondrial function, improving energy production and reducing oxidative stress. It has shown potential in supporting cardiovascular health, protecting against neurodegenerative diseases, and enhancing muscle function, making it ideal for those looking to improve overall cell health and energy. If you’re looking to buy SS-31, visit https://buypeptidesaustralia.com for high-quality peptides with fast shipping across Australia. Boost your mitochondrial health with SS-31 and experience the benefits today!
What Is SS-31 ?
SS-31, also known as Elamipretide, is a synthetic peptide designed to target and improve mitochondrial function. It works by stabilizing the mitochondrial membrane and reducing oxidative stress, which helps to enhance energy production within cells. This peptide is primarily studied for its potential to improve cardiovascular health, protect against neurodegenerative diseases, and slow the aging process by addressing mitochondrial dysfunction. The SS-31 has also shown promise in supporting muscle health and preventing damage caused by oxidative stress, making it a valuable option for individuals looking to improve cellular energy and overall well-being.
Why Choose Buy Peptides Australia for Your SS-31 Peptide Research?
In the rapidly expanding fields of mitochondrial biology, cardioprotection, and neurodegeneration research, SS-31 (Elamipretide / Bendavia) has emerged as a groundbreaking tool. As a cell-permeable, mitochondria-targeted tetrapeptide, SS-31 uniquely binds to cardiolipin in the inner mitochondrial membrane, making it an invaluable compound for studying oxidative stress, electron transport chain efficiency, and cellular apoptosis in-vitro.
However, SS-31 is not a standard peptide. Its unique sequence incorporates non-standard and D-amino acids (D-Arginine and 2′,6′-dimethyl-L-tyrosine). If the synthesis is flawed, the peptide will fail to cross the mitochondrial membrane or bind to cardiolipin, rendering your assays useless. When sourcing SS-31, Buy Peptides Australia is the definitive choice for laboratories demanding absolute sequence fidelity and bioactivity.
Here is why leading Australian researchers trust us for their SS-31 requirements.
1. Precise Synthesis of Modified Amino Acids
The biological efficacy of SS-31 relies entirely on its specific modified sequence (D-Arg-Dmt-D-Arg-Phe-NH2). Standard peptide synthesis errors will result in a compound that cannot target the mitochondria.
- Exact Sequence Fidelity: Our synthesis protocols strictly utilize high-grade, verified D-amino acids and dimethyltyrosine (Dmt) to ensure the exact structural conformation required for mitochondrial targeting.
- Amidation: The C-terminus of SS-31 is properly amidated during synthesis, which is critical for its cell-permeability and resistance to enzymatic degradation in cell culture media.
2. Ultra-High Purity and Rigorous Analytical Testing
In cellular and mitochondrial assays, even trace impurities can generate confounding oxidative stress or interfere with fluorescence-based assays.
- ≥ 98.0% Purity: We guarantee a minimum purity of 98% for our SS-31, verified via High-Performance Liquid Chromatography (HPLC).
- Mass Spectrometry (MS) Verified: Every batch is analyzed via MS to confirm the exact molecular weight of the modified tetrapeptide.
- Transparent CoAs: We provide batch-specific Certificates of Analysis with actual chromatograms, allowing you to verify the exact quality and purity of the reagent you are using.
3. Advanced Lyophilization for Maximum Stability
While SS-31 is more stable than many natural peptides due to its D-amino acids, improper lyophilization can still lead to clumping and reduced solubility.
- Controlled Freeze-Drying: Our SS-31 is lyophilized under strictly controlled, sterile, and inert conditions to preserve its structural integrity and ensure it dissolves rapidly and completely upon reconstitution.
- Climate-Controlled Warehousing: We store all our peptides in temperature-monitored, low-humidity environments, ensuring the compound remains perfectly stable from our facility to your laboratory bench.
4. Fast, Secure, and 100% Domestic Australian Shipping
Importing specialized research peptides from overseas exposes them to extreme temperature fluctuations and risks lengthy customs delays.
- Local Stock: Our SS-31 is warehoused locally in Australia, meaning your order is dispatched immediately.
- Rapid & Discreet Delivery: We utilize premium domestic couriers and ship all orders in plain, unmarked packaging to ensure security, privacy, and rapid delivery directly to your lab door.
5. Expert Peptide Handling and Reconstitution Support
Although SS-31 is highly water-soluble, proper handling is still required to maintain its bioactivity in sensitive mitochondrial assays.
- Technical Guidance: The team at Buy Peptides Australia consists of peptide specialists. We provide clear, scientifically accurate reconstitution protocols to ensure your peptide is prepared correctly for your specific cell culture or in-vitro models.
- Dedicated Support: Whether you need advice on aliquoting, storage temperatures, or assay preparation, our team is here to assist you.
The Research Value of SS-31 (Elamipretide)
SS-31 is a highly specialized compound utilized in cutting-edge biochemical research. Its unique mechanism allows researchers to conduct studies that are difficult to perform with general antioxidants:
- Cardiolipin Stabilization: Investigating the protection and remodeling of the inner mitochondrial membrane in models of cellular stress.
- Reactive Oxygen Species (ROS) Reduction: Studying the targeted scavenging of superoxide and the reduction of oxidative damage at the source (the electron transport chain).
- Ischemia-Reperfusion Injury: Analyzing cardioprotective and neuroprotective pathways in in-vitro models of oxygen-glucose deprivation and reperfusion.
- Mitochondrial Permeability Transition Pore (mPTP): Researching the prevention of mPTP opening and subsequent cellular apoptosis.
TECHNICAL DATA SHEET (TDS)
Product Name: SS-31 Peptide (Elamipretide)
Synonyms: Bendavia, MTP-131, Elamipretide, Mitochondria-Targeted Peptide SS-31
CAS Number: 1138164-57-6
Classification: Cell-permeable, mitochondria-targeted tetrapeptide
Intended Use: Strictly for in-vitro and preclinical laboratory research. NOT for human or veterinary consumption.
Synonyms: Bendavia, MTP-131, Elamipretide, Mitochondria-Targeted Peptide SS-31
CAS Number: 1138164-57-6
Classification: Cell-permeable, mitochondria-targeted tetrapeptide
Intended Use: Strictly for in-vitro and preclinical laboratory research. NOT for human or veterinary consumption.
1. Chemical & Physical Properties
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Parameter
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Specification
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Appearance
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White to off-white, sterile, lyophilized (freeze-dried) powder.
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Amino Acid Sequence
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H-D-Arg-Dmt-D-Arg-Phe-NH2 (Dmt = 2′,6′-dimethyl-L-tyrosine; C-terminally amidated).
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Molecular Formula
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C₃₇H₅₈N₁₂O₆
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Molecular Weight
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~784.9 g/mol
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Counter Ion
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Trifluoroacetate (TFA) or Acetate (Typically < 10% by weight).
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Solubility
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Highly soluble in sterile distilled water, PBS, and cell culture media due to the presence of multiple arginine residues and C-terminal amidation.
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2. Analytical & Quality Control Data
Because SS-31 incorporates non-standard and D-amino acids, rigorous testing is required to ensure sequence fidelity and proper amidation.
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Test Parameter
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Acceptance Criteria
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Typical Result
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|---|---|---|
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Purity (HPLC)
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≥ 98.0%
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98.5% – 99.5%
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Peptide Content
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≥ 85.0% (by weight, excluding moisture and salts)
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88% – 92%
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Moisture Content (Karl Fischer)
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≤ 5.0%
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< 3.0%
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Identification (Mass Spectrometry)
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Matches theoretical molecular weight of SS-31 (± 0.5 Da)
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Confirmed
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Acetate/TFA Content
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< 10.0% (by Ion Chromatography)
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Pass
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Bacterial Endotoxins
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< 1.0 EU/mg (Research Grade)
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< 0.5 EU/mg
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3. Handling, Storage & Reconstitution Guidelines
While SS-31 is highly stable and water-soluble compared to many natural peptides, proper handling is required to maintain its bioactivity in sensitive cellular assays.
- Long-Term Storage (Lyophilized): Store at -20°C in a dark, dry, airtight environment. Under these conditions, the peptide remains stable for 24+ months.
- Short-Term Storage (Lyophilized): Stable at 2°C to 8°C for up to 4 weeks.
- Reconstitution Protocol:
- Allow the vial to reach room temperature before opening to prevent moisture condensation.
- Add sterile distilled water, PBS, or cell culture media directly to the vial.
- Gently swirl the vial until the powder is completely dissolved. Do not vortex vigorously, as excessive foaming can introduce air-liquid interface stress.
- Storage (Reconstituted): Store aliquots at -20°C for long-term use. Reconstituted solutions kept at 2°C to 8°C should be used within 7–14 days. Avoid repeated freeze-thaw cycles.
4. Biological Activity & Research Applications
- Mechanism of Action: SS-31 utilizes a highly conserved aromatic-cationic motif to selectively target and accumulate in the inner mitochondrial membrane (IMM). Once inside, it specifically binds to cardiolipin, a unique phospholipid essential for the structural integrity of the electron transport chain (ETC) complexes.
- Key Research Advantages:
- Cell Permeability: Unlike many mitochondrial antioxidants, SS-31 readily crosses the plasma membrane and mitochondrial membranes without requiring conjugation to a carrier molecule.
- Targeted Action: It does not scavenge ROS indiscriminately in the cytosol; instead, it stabilizes cardiolipin, preventing the release of cytochrome c and reducing ROS production specifically at the source (the ETC).
- Primary Research Applications:
- Ischemia-Reperfusion Injury: Studying cardioprotective and neuroprotective pathways in in-vitro models of oxygen-glucose deprivation.
- Oxidative Stress & Apoptosis: Analyzing the reduction of mitochondrial reactive oxygen species (mROS) and the prevention of mitochondrial permeability transition pore (mPTP) opening.
- Cardiolipin Remodeling: Investigating the protection of the IMM in models of cellular stress, aging, and metabolic dysfunction.
- Neurodegeneration Models: Evaluating mitochondrial rescue in in-vitro models of Parkinson’s, Alzheimer’s, and other neurodegenerative conditions.
5. Regulatory & Safety Disclaimer
⚠️ FOR RESEARCH USE ONLY (RUO)
This product is intended solely for in-vitro laboratory research, forensic analysis, and preclinical scientific studies.
This product is intended solely for in-vitro laboratory research, forensic analysis, and preclinical scientific studies.
- Not for Human Use: This product is NOT intended for diagnostic, therapeutic, or clinical use in humans or animals. It is an investigational compound and has not been approved by the Therapeutic Goods Administration (TGA), FDA, EMA, or any other regulatory body for human consumption.
- Handling: Always use appropriate Personal Protective Equipment (PPE), including lab coats, nitrile gloves, and safety goggles. Handle reconstitution in a certified chemical fume hood or biosafety cabinet.
- Compliance: The buyer is solely responsible for ensuring that the purchase, possession, and use of this compound comply with all applicable local, state, and federal laws, as well as institutional review board (IRB) or animal ethics committee guidelines.
6. Documentation Provided with Every Batch
To ensure full traceability and research integrity, every order of SS-31 includes:
- Certificate of Analysis (CoA) featuring actual HPLC chromatograms and Mass Spectrometry (MS) reports for the specific batch.
- Material Safety Data Sheet (MSDS / SDS).
- Handling and Reconstitution Guide.
SS-31 Peptide
SS-31 peptide, also known as Elamipretide, is a synthetic compound that targets mitochondrial health to improve energy production. It works by reducing oxidative stress within cells, enhancing their overall function. Known for its potential to support cardiovascular, neurodegenerative, and muscle health, SS-31 peptide offers a promising solution for improving cellular energy and longevity.
How Does SS-31 Work
SS-31 works by targeting the mitochondria, the energy-producing structures within cells. It binds to the inner mitochondrial membrane, stabilizing its structure and improving its function. This enhances the mitochondrial membrane potential, which boosts cellular energy production. Additionally, SS-31 reduces oxidative stress by neutralizing reactive oxygen species (ROS) within the mitochondria, preventing cellular damage. As a result, SS-31 helps improve energy production, supports tissue repair, and protects against oxidative damage, benefiting organs and systems that rely heavily on mitochondrial function, such as the heart and brain.
SS-31 Side Effects
SS-31 is generally considered safe, but like any supplement or peptide, it may cause side effects in some individuals. Common side effects are usually mild and may include:
- Headaches: Some users report mild headaches, especially when starting SS-31.
- Nausea or Digestive Issues: Gastrointestinal discomfort like nausea or stomach upset can occur.
- Fatigue or Dizziness: Some users may feel lightheaded or experience a drop in energy, especially in the early stages of use.
These side effects are typically temporary, but if they persist or worsen, it’s important to consult with a healthcare professional. Always follow recommended dosages and consult with a doctor before using SS-31, especially if you have underlying health conditions.
SS-31 Peptide Benefits
SS-31 peptide offers a range of potential benefits, primarily due to its ability to improve mitochondrial function and reduce oxidative stress. Some of the key benefits include:
- Improved Cardiovascular Health: SS-31 can enhance heart health by boosting mitochondrial function in heart cells, potentially benefiting those with heart failure, ischemia, and other cardiovascular issues.
- Neuroprotective Effects: By improving mitochondrial function in brain cells, SS-31 may help protect against neurodegenerative diseases like Alzheimer’s and Parkinson’s, reducing cognitive decline and supporting overall brain health.
- Anti-Aging: SS-31 may slow the aging process by addressing mitochondrial dysfunction, which naturally declines with age. This could help preserve muscle function, improve energy levels, and reduce signs of aging.
- Muscle Health: SS-31 may improve muscle function and recovery by enhancing energy production within muscle cells, benefiting athletes or individuals experiencing muscle weakness or fatigue.
- Reduction in Oxidative Stress: By neutralizing reactive oxygen species (ROS), SS-31 reduces oxidative damage, which is linked to aging, inflammation, and chronic diseases.
Overall, SS-31 peptide can support cellular energy, protect against cellular damage, and improve the function of key organs, including the heart and brain.
IMPORTANT LEGAL AND SAFETY DISCLAIMER
PLEASE READ CAREFULLY BEFORE PURCHASING OR HANDLING SS-31 (ELAMIPRETIDE)
1. STRICTLY FOR RESEARCH USE ONLY (RUO)
SS-31 (Elamipretide / Bendavia) supplied by Buy Peptides Australia is strictly classified as a research chemical. It is intended solely for in-vitro laboratory research, preclinical scientific studies, and forensic analysis. This product is NOT a drug, dietary supplement, food, or cosmetic.
2. NOT FOR HUMAN OR ANIMAL CONSUMPTION
UNDER NO CIRCUMSTANCES is SS-31 to be administered to humans or animals.
- No Injections or Ingestion: This product is NOT intended for human or veterinary injection, ingestion, inhalation, or topical application.
- Any misuse of this product for self-administration, clinical therapy, or veterinary use is strictly prohibited, highly dangerous, and is done entirely at the user’s own risk. Buy Peptides Australia explicitly forbids the use of this product for human consumption.
3. NO BIOHACKING, LONGEVITY, OR ANTI-AGING CLAIMS
No information, text, graphics, or materials provided by Buy Peptides Australia regarding SS-31 are intended to promote mitochondrial health, cellular energy, longevity, life extension, anti-aging, or biohacking in humans.
- The information provided is for in-vitro educational and scientific reference only (e.g., studying cardiolipin stabilization, reactive oxygen species reduction, and ischemia-reperfusion models in cell cultures).
- It should not be construed as medical, longevity, or performance-enhancing advice.
4. INVESTIGATIONAL STATUS AND REGULATORY COMPLIANCE
SS-31 is an investigational compound currently undergoing clinical evaluation. It has NOT been approved by the Therapeutic Goods Administration (TGA) in Australia, the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), or any other global regulatory body for medical, therapeutic, or commercial use.
- Prescription & Trial Status: As an investigational new drug, it is illegal to supply or possess this substance for human use outside of authorized, regulated clinical trials.
- The buyer is solely responsible for ensuring that the purchase, possession, handling, and use of SS-31 comply with all applicable local, state, and federal laws and regulations.
5. ASSUMPTION OF RISK AND LIMITATION OF LIABILITY
By purchasing SS-31, the buyer acknowledges that they are handling a potent, experimental biochemical compound.
- The buyer assumes all risks associated with the handling, storage, reconstitution, and disposal of this product.
- Buy Peptides Australia, its directors, employees, and affiliates shall not be held liable for any direct, indirect, incidental, consequential, or punitive damages, injuries, or legal actions arising from the use, misuse, or inability to use this product.
- The buyer agrees to indemnify and hold harmless Buy Peptides Australia from any claims or liabilities arising from the buyer’s failure to adhere to this disclaimer, including the unauthorized human administration of this product.
6. BUYER ELIGIBILITY AND VETTING
Purchasers must be of legal adult age and must be qualified researchers, academic institutions, licensed laboratories, or authorized scientific personnel.
- Due to the high potential for misuse of SS-31 by the “biohacking” and longevity communities, Buy Peptides Australia reserves the right to refuse service, cancel orders, or request proof of institutional affiliation (e.g., a laboratory license, university ID, or business ABN) at our sole discretion.
- We actively monitor for and will ban individuals attempting to purchase this product for personal, non-laboratory use.
7. SAFE HANDLING AND PROTOCOLS
SS-31 must be handled in accordance with standard laboratory safety protocols.
- Always use appropriate Personal Protective Equipment (PPE), including lab coats, nitrile gloves, and safety goggles.
- Reconstitution and handling should be performed in a certified chemical fume hood or biosafety cabinet.
- Ensure proper disposal of all peptide waste in accordance with local environmental and hazardous waste regulations.
BY COMPLETING YOUR PURCHASE, YOU ACKNOWLEDGE THAT YOU HAVE READ, UNDERSTOOD, AND AGREED TO ALL TERMS STATED IN THIS DISCLAIMER, AND YOU CONFIRM THAT YOU ARE PURCHASING SS-31 SOLELY FOR LAWFUL IN-VITRO RESEARCH PURPOSES.
Thomas King –
Really pleased with SS‑31 from buypeptidesaustralia.com! It’s made a difference in how I feel day‑to‑day, more clarity and less mid‑day slump. It’s not dramatic, but it’s definitely noticeable. Great quality and quick shipping.
Lily Green –
I started using SS‑31 from this store a few weeks ago, and I’ve been genuinely impressed. My energy feels more consistent throughout the day, and I’m not crashing like I used to. It’s subtle, but I honestly feel more focused and alert, plus the delivery was really quick!
William Wright –
SS‑31 from buypeptidesaustralia.com has helped with my recovery after workouts. I used to feel sore for days, but now I’m getting back into training faster. It took a little time to notice, but the steady improvements have been worth it!
Ruby Scott –
I ordered SS‑31 through this website, and I did notice some mild benefits, a bit more energy and less fatigue, but the results were slower and gentler than I expected. Still happy with the ordering process and delivery.